CJC-1295 is a growth-hormone-releasing hormone (GHRH) analog studied as a research secretagogue — available in a shorter-acting no-DAC form and a long-acting DAC form.
What is CJC-1295?
CJC-1295 is a synthetic analog of growth-hormone-releasing hormone (GHRH), based on the first 29 amino acids of GHRH (GRF 1-29) with substitutions that increase stability. It is studied as a research growth-hormone secretagogue acting at the GHRH receptor.
- CJC-1295GHRH(1-29) analogue; DAC variant adds a linker
- GHRH receptorPituitary somatotrophs
- Gs → cAMP → PKADAC binds albumin, extending half-life to days
- GH secretion modelsPreclinical and early clinical
Mechanism as described in published research. Nothing here describes an effect in a person — these compounds are supplied for laboratory research use only.
No DAC vs DAC
CJC-1295 comes in two research forms. The no-DAC form (also called Mod GRF 1-29 or CJC-1295 without DAC) is shorter-acting. The DAC form adds a Drug Affinity Complex that binds albumin, dramatically extending the research half-life for sustained-signaling studies.
How CJC-1295 is studied
Both forms are investigated for GHRH-receptor signaling and growth-hormone-release pathways:
- GHRH-receptor activation and downstream GH release.
- Pulsatile vs sustained signaling (no-DAC vs DAC).
- Secretagogue combination research with ghrelin mimetics.
Half-life & forms
The no-DAC form has a short research half-life (roughly 30 minutes), while the DAC form extends to the order of a week thanks to albumin binding. Both ship lyophilized.
Commonly studied alongside
CJC-1295 is classically paired with the selective ghrelin mimetic Ipamorelin (overview), and is offered as the CJC-1295 + Ipamorelin blend. Reconstitute with bacteriostatic water — see the reconstitution guide.
Frequently asked questions
What is CJC-1295?
CJC-1295 is a GHRH analog (based on GRF 1-29) studied as a research growth-hormone secretagogue at the GHRH receptor.
What is the difference between CJC-1295 no DAC and DAC?
The no-DAC form is shorter-acting (half-life ~30 minutes); the DAC form adds a Drug Affinity Complex that binds albumin and extends the half-life to about a week, for sustained-signaling research.
What is CJC-1295 studied with?
It is most often co-studied with ipamorelin, a selective ghrelin-receptor agonist, and is available as a blend.
Is CJC-1295 lab-tested?
Yes — every lot is lab-tested to a 99%+ purity standard with a batch-specific Certificate of Analysis published in full.
Why researchers order from Miami Peptide Lab
- Independently tested every lot — the batch Certificate of Analysis is published in full, free to read.
- Ships from Miami and across the US in 24–48 business hours with tracking, in discreet cold-chain packaging.
- Buy-more-save-more bundle pricing on every vial, plus a reship-or-refund guarantee.
Research use only
All products referenced here are sold strictly for laboratory and research use. They are not intended for human or animal consumption, nor for any therapeutic, diagnostic, or cosmetic use, and must be handled only by qualified professionals in an appropriate research setting.
