Retatrutide and tirzepatide are both multi-receptor metabolic research peptides — the difference is how many receptors they engage. Tirzepatide is a dual GIP/GLP-1 agonist; retatrutide adds a third target, the glucagon receptor, making it a triple agonist.
Tirzepatide (dual agonist)
Tirzepatide engages GIP and GLP-1 receptors, studied widely in metabolic and glycemic research.
Retatrutide (triple agonist)
Retatrutide is a GIP / GLP-1 / glucagon receptor agonist — the “triple-G” — studied for the combined action of three metabolic pathways.
Key research differences
| Receptor targets | Tirzepatide: GIP + GLP-1 · Retatrutide: GIP + GLP-1 + glucagon |
|---|---|
| Class | Tirzepatide: dual agonist · Retatrutide: triple agonist |
Also compare Tirzepatide vs Semaglutide.
Shop RetatrutideShop Tirzepatide
Why researchers buy from Miami Peptide Lab
- 99%+ purity, lab-tested every lot — Certificate of Analysis published in full
- Ships from Miami / the US in 24–48h, discreet cold-chain packaging
- Buy-more-save-more bundle pricing, and a reship-or-refund guarantee
Research Use Only. All compounds are sold strictly for laboratory research and are not for human or animal consumption, nor for therapeutic, diagnostic, or cosmetic use.
