BPC-157 is one of the most extensively studied peptides in preclinical tissue-repair research — a stable synthetic pentadecapeptide investigated across gastrointestinal, tendon, and angiogenesis models.
What is BPC-157?
BPC-157 (Body Protection Compound-157, also seen as PL 14736 or Bepecin) is a synthetic pentadecapeptide — a chain of 15 amino acids. Its sequence corresponds to a partial fragment of a protein identified in human gastric juice, and it is notable in the research literature for its stability in gastric acid, which is unusual for a peptide of its size. Because of that stability it is frequently referred to as a “stable gastric pentadecapeptide.”
Structure & background
The peptide carries the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val and a molecular weight of roughly 1,419 Da. It first appeared in preclinical research in the 1990s and has since been the subject of a large body of animal-model work, much of it associated with research groups studying gastrointestinal protection and the gut-brain axis. It does not occur as an isolated peptide in nature — it is a synthesized fragment created for research.
What BPC-157 is studied for
In laboratory and animal models, BPC-157 is investigated for a range of tissue-repair and cytoprotective pathways. Reported research directions include:
- Angiogenesis — formation of new blood vessels, studied in part through the VEGFR2 signaling pathway.
- Tendon, ligament, and muscle models — including work on fibroblast outgrowth and cell migration.
- Gastrointestinal research — ulcer, mucosal, and inflammatory-bowel models, reflecting its gastric-juice origin.
- Nitric oxide (NO) system — interaction with NO signaling is a recurring theme in the literature.
- Neuroprotection and the gut-brain axis — exploratory work in neurological models.
These are descriptions of research directions in preclinical models, not outcomes in humans.
Forms & half-life
BPC-157 is supplied as a lyophilized (freeze-dried) powder. Its circulating half-life in research models is short, which is one reason study protocols vary widely. A related arginine-salt form (“BPC-157 arginate”) also appears in the literature; the material sold here is the standard acetate lyophilized form.
Reconstitution, handling & storage
BPC-157 ships lyophilized and is reconstituted with bacteriostatic water. Sealed vials are stored cold and protected from light; reconstituted material is refrigerated. For the full procedure and stability details, see the reconstitution guide, the reconstitution calculator, and the storage & stability guide.
Commonly studied alongside
BPC-157 is frequently co-studied with TB-500 in recovery research (see BPC-157 vs TB-500) and with the copper peptide GHK-Cu. It is also available as the BPC-157 + TB-500 blend. For the broader category, see the healing & recovery peptides guide.
Frequently asked questions
What is BPC-157?
BPC-157 is a synthetic 15-amino-acid peptide (a "stable gastric pentadecapeptide") whose sequence derives from a protein found in gastric juice. It is studied in preclinical tissue-repair, gastrointestinal, and angiogenesis research.
What is BPC-157 studied for?
In animal and laboratory models it is investigated for angiogenesis, tendon/ligament/muscle repair pathways, gastrointestinal protection, and nitric-oxide signaling. These are research directions, not human outcomes.
How is BPC-157 reconstituted?
BPC-157 ships as a lyophilized powder and is reconstituted with bacteriostatic water, then refrigerated. See our reconstitution guide and calculator for exact volumes.
BPC-157 vs TB-500 — what is the difference?
BPC-157 is a gastric-derived pentadecapeptide; TB-500 is a synthetic fragment of thymosin beta-4. They are often co-studied in recovery research. See our full BPC-157 vs TB-500 comparison.
Is BPC-157 lab-tested?
Every Miami Peptide Lab lot is lab-tested to a 99%+ purity standard, with a batch-specific Certificate of Analysis available on request.
Why researchers order from Miami Peptide Lab
- 99%+ purity, lab-tested every lot — a batch-specific COA is available on request.
- Ships from Miami and across the US in 24–48 business hours with tracking, in discreet cold-chain packaging.
- Buy-more-save-more bundle pricing on every vial, plus a reship-or-refund guarantee.
Research use only
All products referenced here are sold strictly for laboratory and research use. They are not intended for human or animal consumption, nor for any therapeutic, diagnostic, or cosmetic use, and must be handled only by qualified professionals in an appropriate research setting.
