Description
MOTS-C (Mitochondrial-derived peptide) is a mitochondrial-derived peptide encoded within the 12S rRNA region. It is studied in metabolic and exercise-physiology research, including work on AMPK signaling and insulin sensitivity.
What researchers study
- AMPK and metabolic signaling
- Mitochondrial and exercise-physiology research
- Insulin-sensitivity models
Handling & storage
Supplied as a lyophilized powder for reconstitution with bacteriostatic water (not included). Store at −20 °C (−4 °F), protected from light. Every lot is independently tested against a 99%+ purity release target, and the batch Certificate of Analysis is published in full on this page.
Research Use Only (RUO). Not for human or animal consumption, nor for therapeutic, diagnostic, or cosmetic use; to be handled only by qualified professionals in a controlled research setting.
Identity and specification
MOTS-C is also referred to as Mitochondrial ORF of the 12S rRNA type-c. It has the molecular formula C101H152N28O22S2 and a molecular weight of 2174.6 g/mol (CAS 1627580-64-6). That weight is corroborated by the mass-confirmation peak on this product’s own certificate rather than quoted from a reference alone.
How this lot was tested
The MOTS-C currently in stock measured 99.06% for the 20 mg (lot 261807), tested by Freedom Diagnostics. The full certificate is published on this site as a free download — including the raw chromatogram and mass spectrum, so the figure can be read off the underlying data rather than taken on trust.
We use two independent laboratories, and each certificate says which produced it. Vanguard Laboratory is ISO 17025:2017 accredited (A2LA certificate #6377.01.01) and reports chromatographic purity and net quantity with a stated measurement uncertainty. Freedom Diagnostics reports HPLC-UV purity together with LC-MS identity confirmation, which is what verifies the vial contains the compound on the label rather than merely a pure something. Two laboratories, two methods, both published — see how we test.
Commonly studied alongside
In the literature MOTS-C is most often examined together with NAD+, SS-31 (Elamipretide) and 5-Amino-1MQ. Reconstitution is the same for all of them — see the reconstitution guide and the calculator, and the storage guide for how long reconstituted material holds. Current pricing for every compound and size is on the price list.
Why researchers order MOTS-C from Miami Peptide Lab
- Independently tested every lot — the batch Certificate of Analysis is published in full, free to read
- Ships from Miami / the US in 24–48 business hours with tracking, in discreet cold-chain packaging
- Buy-more-save-more pricing — automatic bundle discounts on multiple vials
- Reship-or-refund guarantee if your order is lost, seized, or arrives damaged




